In a medium bowl, combine the ground beef, bread crumbs, onion, egg, garlic, adobo sauce, cumin, oregano, salt, and pepper. Mix until well combined.
Form the mixture into small meatballs and set aside.
In a large pot over medium heat, heat the oil. Add the meatballs and cook until browned, about 5 minutes.
Add the flour and stir until well combined. Cook for 1 minute.
Slowly add the milk, stirring constantly to prevent lumps. Bring to a simmer and cook until the sauce is thickened, about 5 minutes.
Stir in the cheddar cheese, chipotle peppers, cayenne pepper, smoked paprika, garlic powder, onion powder, basil, thyme, and oregano. Stir until the cheese is melted and the sauce is smooth.
Add the cooked macaroni and stir until combined. Season with salt and pepper to taste.
Serve the macaroni and cheese warm, topped with the adobo meatballs.
Interesting Facts
Adobo sauce is a spicy Mexican sauce made from tomatoes, onions, garlic, and a variety of spices.
Chipotle peppers are smoked jalapeno peppers that are canned in adobo sauce.
Smoked paprika is a type of paprika that has been smoked over a wood fire, giving it a smoky flavor.