In a medium saucepan, combine the guava juice, ketchup, apple cider vinegar, Worcestershire sauce, black pepper, thyme, oregano, garlic powder, onion powder, red pepper flakes, and cayenne pepper.
Bring to a simmer and cook over medium heat for 10 minutes, stirring occasionally.
Add the brown sugar and stir until completely dissolved.
Continue to cook for an additional 10 minutes, stirring occasionally.
Remove from heat and let cool to room temperature.
Pour the sauce into a jar or container and store in the refrigerator for up to 2 weeks.
Interesting Facts
Guava juice is high in Vitamin C and antioxidants.
The guava flavor adds a unique sweetness to the barbeque sauce.
This sauce is perfect for grilling meats, vegetables, and more!