In a shallow dish, mix together the flour, garlic powder, onion powder, smoked paprika, salt, black pepper, and cayenne pepper.
In a separate shallow dish, pour the buttermilk.
Dip each piece of chicken into the buttermilk and then into the flour mixture, making sure to coat each piece evenly.
In a large skillet over medium heat, add the vegetable oil and heat until it reaches 350°F.
Carefully add the chicken pieces to the hot oil and fry for 8-10 minutes, flipping each piece halfway through cooking, until they are golden brown and cooked through.
Transfer the fried chicken to a paper towel-lined plate and let rest for a few minutes before serving.
Interesting Facts
Fried chicken is thought to have originated in Scotland, where it was a popular dish in the 18th century.
Southern fried chicken is believed to have been brought to the United States by African-American slaves.
Fried chicken is a popular dish in many parts of the world, including the United States, the United Kingdom, South Korea, and Jamaica.