Preheat oven to 350 degrees F. Grease a 9x13-inch baking dish.
In a large bowl, whisk together the cream of mushroom soup, milk, butter, garlic powder, onion powder, salt and pepper. Stir in the tuna, egg noodles, vegetables, and mushrooms.
Pour the mixture into the prepared baking dish and sprinkle with the cheese.
Bake for 40-45 minutes, or until the top is golden brown and the casserole is bubbling.
Let cool for 10 minutes before serving.
Interesting Facts
Tuna noodle casserole is a classic American dish that has been enjoyed for generations.
It is an easy and tasty dish that can be made with just a few pantry staples.
This dish can be served as a main dish or a side dish.