Mix together the smoked paprika, garlic powder, oregano, onion powder, brown sugar, salt, and pepper in a small bowl. Rub the mixture over the pork loin.
Place pork loin in an oven-safe dish and bake for 25 minutes.
Meanwhile, mix together the ketchup, apple cider vinegar, Worcestershire sauce, honey, and mustard in a small bowl.
Remove pork loin from oven and brush the sauce over the pork loin. Return to oven and bake for an additional 20 minutes.
Remove from oven and let cool before slicing. Serve on a sandwich or in tacos.
Interesting Facts
Pork loin is a lean cut of pork that is low in fat and calories.
Smoked paprika is a type of paprika made from smoked, dried peppers.
Apple cider vinegar is a type of vinegar made from fermented apples.