In a medium bowl, mix together the ketchup, brown sugar, apple cider vinegar, Worcestershire sauce, smoked paprika, garlic powder, onion powder, black pepper, ground mustard, celery seed, cayenne pepper, and salt.
Place the brisket in a large baking dish and pour the ketchup mixture over the top. Flip the brisket over to make sure it is fully coated.
Cover the dish tightly with aluminum foil and bake for 2 hours, or until the brisket is tender and juicy.
Serve hot or cold.
Interesting Facts
Brisket is a cut of meat from the breast or lower chest of beef.
Brisket can be cooked in a variety of ways, including roasting, braising, and smoking.
Brisket is a popular dish in Jewish and Central European cuisine.