In a large bowl, mix together the ground beef, bread crumbs, onion, bell pepper, BBQ sauce, ketchup, Worcestershire sauce, smoked paprika, garlic powder, onion powder, chili powder, cumin, cayenne pepper, salt, and pepper.
Form the mixture into a loaf shape and place in a greased 9x13 inch baking dish.
Bake for 45 minutes, or until the internal temperature reaches 160 degrees Fahrenheit.
Let the meatloaf rest for 10 minutes before slicing and serving.
Interesting Facts
Smoked paprika gives this meatloaf its distinct flavor.
Ground beef is high in protein, iron, and vitamin B12.
This dish is a great way to use up leftover vegetables.