In a large bowl, combine the ground beef, diced onion, diced bell pepper, cheddar cheese, bread crumbs, egg, garlic powder, onion powder, salt, and black pepper.
Mix together until fully combined.
Shape the mixture into a loaf and place it in a greased baking dish.
Spread the ketchup over the top of the meatloaf.
Bake for 1 hour, or until the internal temperature reaches 165F degrees.
Let cool for 10 minutes before slicing and serving.
Interesting Facts
Meatloaf is a traditional American dish that dates back to the 19th century.
Onion and pepper are a classic combination in American cuisine.
Adding cheese to the meatloaf mixture adds a delicious flavor and helps keep the meatloaf moist.