In a medium saucepan over medium heat, add the ketchup, brown sugar, apple cider vinegar, molasses, Worcestershire sauce, yellow mustard, garlic powder, onion powder, smoked paprika, black pepper, and cayenne pepper.
Bring the mixture to a boil, then reduce heat to low and simmer for 10-15 minutes, stirring occasionally.
Remove from heat and allow to cool before using.
Interesting Facts
Barbecue sauce originated in the Caribbean in the 17th century.
The most popular barbecue sauces are tomato-based, but there are also mustard-based, vinegar-based, and even mayonnaise-based sauces.
Barbecue sauce is used for both grilling and baking, and can be used as a marinade, a dipping sauce, or a condiment.