Heat olive oil in a large skillet over medium heat. Add onion, bell peppers, garlic, oregano, basil, salt, pepper, and red pepper flakes (if using). Cook for 5 minutes, stirring occasionally, until vegetables are softened.
Add white wine and cook for 1 minute.
Add kale and roasted vegetables and cook for an additional 2 minutes.
Remove from heat and stir in ricotta, Parmesan, and 1/4 cup of mozzarella.
Spread 1/2 cup of the vegetable mixture in the bottom of a 9x13 inch baking dish.
Arrange 3 lasagna noodles over the vegetable mixture. Top with 1/3 of the remaining vegetable mixture. Repeat layering twice more, ending with noodles.
Pour cream over the top of the lasagna.
Sprinkle with remaining mozzarella cheese.
Cover with aluminum foil and bake for 40 minutes.
Remove foil and bake for an additional 20 minutes, until cheese is golden brown and bubbly.
Let cool for 10 minutes before serving.
Interesting Facts
Lasagna is an Italian dish traditionally made with layers of cheese, noodles, and a meat sauce.
This version is vegetarian, but you can add cooked ground beef or Italian sausage for a heartier dish.
You can use any type of roasted vegetables you like in this lasagna.